Exhibit 23.1


Consent of Independent Registered Public Accounting Firm


Avenue Therapeutics, Inc.

Bay Harbor Islands, FL


We hereby consent to the incorporation by reference in this Registration Statement on Form S-8 of our report dated March 25, 2022, relating to the financial statements of Avenue Therapeutics, Inc. appearing in the Company’s Annual Report on Form 10-K for the year ended December 31, 2021. Our report contains an explanatory paragraph regarding the Company’s ability to continue as a going concern.




New York, New York


February 10, 2023