Annual report pursuant to Section 13 and 15(d)

Document and Entity Information

Document and Entity Information - USD ($)
12 Months Ended
Dec. 31, 2021
Mar. 21, 2022
Jun. 30, 2021
Document and Entity Information [Abstract]      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2021    
Entity Registrant Name AVENUE THERAPEUTICS, INC.    
Document Transition Report false    
Entity File Number 001-38114    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 47-4113275    
Entity Address, Address Line One Delaware    
Entity Address, City or Town New York    
Entity Address, State or Province NY    
Entity Address, Postal Zip Code 10036    
City Area Code 781    
Local Phone Number 652-4500    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company true    
Entity Shell Company false    
Entity Public Float     $ 16,813,403
Entity Common Stock, Shares Outstanding   21,732,284  
Entity Central Index Key 0001644963    
Current Fiscal Year End Date --12-31    
Document Fiscal Year Focus 2021    
Document Fiscal Period Focus FY    
Amendment Flag false    
Title of 12(b) Security Common Stock, par value $0.0001 per share    
Trading Symbol ATXI    
Security Exchange Name NASDAQ    
Entity Ex Transition Period true    
Auditor Name BDO USA, LLP    
Auditor Firm ID 243    
Auditor Location New York, NY